Nucleic acid isolation · From sample to answer

Norgen Biotek — nucleic acid isolation for every sample type

Norgen Biotek is a Canadian manufacturer of nucleic acid isolation and purification kits. Its catalogue includes more than 500 products for DNA, RNA, miRNA, cfDNA and exosomes. Input material can be blood, plasma, urine, stool, saliva, tissue or environmental samples. The company holds ISO 9001, 13485 and 15189 certifications.

  • 1998 Founded in Canada
  • 500+ Products in the catalogue
  • 155+ Countries where the kits are used
  • 3× ISO Certified to 9001, 13485 and 15189
About the company

Isolation kits since 1998

Norgen Biotek was founded in Canada in 1998. Today it supplies kits to more than 1,000 research institutions and laboratories in over 155 countries. The catalogue contains more than 500 items, from individual consumables to kits covering the entire path from sample collection to result.

Three certifications cover different types of operation: ISO 9001 for quality management, ISO 13485 for medical devices and ISO 15189 for clinical laboratories. Norgen has developed its own silicon carbide spin-column technology, magnetic bead systems and rapid PCR-based diagnostic kits.

Main categories

Five categories from collection to analysis

Collection and stabilisation

Collection and stabilisation

Collection tubes and systems that get the sample from the patient to the laboratory unchanged: blood, saliva, stool, urine and swabs. Nucleic acids remain stable at room temperature.

Nucleic acid isolation

Nucleic acid isolation

Norgen's core portfolio. Isolation of DNA, RNA, miRNA, cfDNA and exosomes from more than 30 sample types, with both spin columns and magnetic beads.

Purification and analysis

Purification and analysis

Post-isolation steps: purification, concentration, normalisation and quantification. These prepare the sample for downstream methods such as PCR, NGS or hybridisation.

Molecular diagnostics

Molecular diagnostics

PCR-based detection kits for bacteria and viruses, as well as for clinically oriented assays. TaqMan chemistry with validated primers and probes.

Laboratory essentials

Laboratory essentials

DNA ladders, enzymes, PCR reagents and nuclease-free water. Consumables for everyday lab work.

Isolation portfolio

Kits grouped by target molecule

Norgen's core portfolio comprises more than 200 isolation kits. They are grouped by what you are isolating and from what. The workflow is consistent across both spin-column and magnetic bead formats.

DNA

DNA isolation kits

Benefits:
Genomic DNA from blood, cells, tissue, plants and microorganisms. Good yield even from small numbers of cells, and purity sufficient for both NGS and PCR.
Use cases:
Whole-genome sequencing, targeted panels, PCR-based diagnostics, forensic genetics, microbial identification.
RNA and miRNA

RNA and miRNA isolation kits

Benefits:
Total RNA as well as small RNA and miRNA. The output is compatible with expression analysis, microarrays and NGS, and sample integrity is preserved.
Use cases:
RNA sequencing, qPCR, miRNA profiling, transcription analysis, single-cell RNA studies.
cfDNA

cfDNA and ctDNA kits

Benefits:
Circulating cell-free DNA from plasma, including tumour-derived DNA (ctDNA). The kits are optimised for low inputs and fragmented DNA. Also available as a sample-to-answer kit.
Use cases:
Liquid biopsy in oncology, resistance monitoring, minimal residual disease detection, prenatal diagnostics.
Exosomes

Exosome and vesicle kits

Benefits:
Isolation of exosomes and extracellular vesicles. Isolation can be followed by RNA and protein analysis.
Use cases:
Biomarker discovery, regenerative medicine, immunotherapy, exosome cargo analysis.
Key advantages

Why laboratories choose Norgen

Good yield from small amounts of material

Proprietary silicon carbide spin-column technology and magnetic bead systems. This matters most for low inputs and limited samples.

Purity for downstream methods

Nucleic acids free of PCR inhibitors and other contaminants. Ready for direct use in NGS, qPCR and hybridisation.

From sample to answer

Norgen covers the entire chain: collection, stabilisation, isolation and detection. One supplier, one point of technical support.

Wide range of sample types

Blood, plasma, serum, urine, stool, saliva, swabs, tissues, cells, biofilms, plants and environmental samples.

Three ISO certifications

ISO 9001, 13485 and 15189 cover research, IVD and clinical laboratories. Regulatory documentation can be provided.

Short, simple protocols

Most kits are completed in 20–60 minutes, with no toxic solvents and no special equipment. They can be automated on Opentrons.

Sample types

Norgen handles even complex samples

It makes no difference whether you work with routine blood or with a sample that standard kits cannot handle. Norgen can cope even with demanding sample types.

Stool and microbiome

Stool and microbiome

The kits stabilise DNA and RNA from stool at room temperature. For gut microbiome, pathogen and gastroenterology studies.

Saliva

Saliva

Non-invasive collection and kits for both DNA and RNA. Used in population studies, forensic genetics and paediatrics.

Urine

Urine

cfDNA, ctDNA and cellular DNA from urine. For urological oncology and non-invasive patient monitoring.

The catalogue also covers blood, plasma, serum, swabs, tissues, cultured cells, biofilms, milk, plant material and environmental samples.

Let's get started

Looking for a Norgen kit for your sample?

We will help you choose based on your sample type, target molecule and the downstream method. We can provide product samples for evaluation, training and technical support.